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Similar to grapefruit, medications known as cytochrome P450 (CP450) inhibitors and substrates can delay how long it takes sildenafil to work and can increase your chance of side effects. These products can raise the levels of sildenafil in your body, but can also delay the time the drug takes effect. The only real food interaction that can occur with generic Viagra is with grapefruit and grapefruit juice. Avoid alcohol if you’re taking sildenafil. AlcoholĪlcohol and sildenafil can combine to lower blood pressure too much. The combination can lower blood pressure, causing fainting, dizziness, and in some rare cases, heart attack. Other ED medicationsĪvoid taking sildenafil with any other ED medications. Severe blood pressure drops can also result in less oxygen moving through your organs.
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Other data pulled from clinical trials in 2016 noted that sildenafil is effective without severe side effects regardless of age. However, for most healthy people, sildenafil can make an erection easier to get.Ī 4-year study published in 2007 found that sildenafil is generally safe to use over the long term. Sildenafil doesn’t trigger an erection on its own, nor does it increase sexual desire. If you take medications for blood pressure control or tend to have low blood pressure, ask your doctor if it’s safe to use sildenafil. Generic Viagra, like other PDE5 inhibitors, can cause a drop in blood pressure. Sildenafil is quickly absorbed into the bloodstream, reaching maximum concentration in about 1 hour for most users. Taking sildenafil improves circulation by helping the arteries relax enough to fill more easily with blood. This is a type of molecule that relaxes smooth muscle tissue in the body, such as those in the blood vessels that allow the penis to become erect. These drugs restrict the action of phosphodiesterase enzymes, which break down cyclic guanosine monophosphate. Sildenafil is in a class of medications called phosphodiesterase type 5 (PDE5) inhibitors. It just helps control blood pressure in the arteries in the lungs.